Griffiths is widely known for her literary portraits, fine art photography, and lyric videos. Her extensive video project, P.O.P (Poets on Poetry), an intimate series of micro-interviews, gathers nearly 100 contemporary poets in conversation, and is featured online by the Academy of American Poets.

When you killed yourself, everything stopped and kept going, and that mixture of inertia and constant motion sent me reeling.

I was the nice-looking, well-dressed woman running down 151st Street in Harlem after school and before evening rush hour on a bright day at the end of August in 2015. If you saw me with my purse half-open and my balance tested more than once, you were wrong to laugh and right to be alarmed.